| Host: |
HEK293 Cells |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Mouse Vitronectin/V75/VTN-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
| Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
Vtn |
| Gene ID: |
22370 |
| Uniprot ID: |
VTNC_MOUSE |
| Immunogen Region: |
Asp20-Lys478 |
| Immunogen: |
Recombinant Mouse Vitronectin/V75/VTN Protein is produced by HEK293 Cells expression system. The target protein is expressed with sequence (Asp20-Lys478) of mouse Vitronectin/V75/VTN (Accession #NP_035837.1) fused with a 6×His tag at the C-terminus. |
| Post Translational Modifications | Sulfated on tyrosine residues. N- and O-glycosylated. It has been suggested that the active SMB domain may be permitted considerable disulfide bond heterogeneity or variability, thus two alternate disulfide patterns based on 3D structures are described with 1 disulfide bond conserved in both. |
| Function | Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway. |
| Protein Name | VitronectinVnS-ProteinSerum-Spreading Factor |
| Database Links | Reactome: R-MMU-2129379Reactome: -MMU-216083Reactome: -MMU-3000170Reactome: -MMU-3000178Reactome: -MMU-977606 |
| Cellular Localisation | SecretedExtracellular Space |
| Alternative Protein Names | Vitronectin proteinVn proteinS-Protein proteinSerum-Spreading Factor proteinVtn protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
