Host: |
HEK293 |
Note: |
STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Recombinant-Mouse uPAR-protein was developed from hek293. For use in research applications. |
Conjugation: |
Unconjugated |
Formulation: |
Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose. |
Dilution Range: |
Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers. |
Storage Instruction: |
Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
Endotoxin: |
Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
Gene Symbol: |
Plaur |
Gene ID: |
18793 |
Uniprot ID: |
UPAR_MOUSE |
Immunogen Region: |
LEU24-THR297 |
Immunogen: |
Optimized DNA sequence encoding Urokinase-type plasminogen activator receptor (LEU24-THR297) including a C-terminal His tag was expressed in HEK293 cells. NA |
Tissue Specificity | Expressed in angiogenic endothelial cells (at protein level). |
Function | Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. |
Protein Name | Urokinase Plasminogen Activator Surface ReceptorU-ParUparCd Antigen Cd87 |
Database Links | Reactome: R-MMU-162791Reactome: -MMU-6798695Reactome: -MMU-75205 |
Cellular Localisation | Isoform 1: Cell MembraneLipid-AnchorGpi-AnchorIsoform 2: Secreted |
Alternative Protein Names | Urokinase Plasminogen Activator Surface Receptor proteinU-Par proteinUpar proteinCd Antigen Cd87 proteinPlaur protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance