Mouse TOP2 (Topoisomerase II) Sandwich ELISA Kit Kit (STJE0012735)

Mouse TOP2 (Topoisomerase II) Sandwich ELISA Kit Kit (STJE0012735)

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STJE0012735
£438.50 - £598.50
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Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.116ng/mL
Detection Limit: 0.312-20ng/mL
Short Description : This TOP2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse tissue homogenates, cell lysates or other biological fluids..
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: Top2a
Gene ID: 21973
Uniprot ID: TOP2A_MOUSE
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity
Post Translational Modifications Phosphorylation has no effect on catalytic activity. However, phosphorylation at Ser-1105 by CSNK1D/CK1 promotes DNA cleavable complex formation.
Function Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand. May play a role in regulating the period length of BMAL1 transcriptional oscillation.
Protein Name Dna Topoisomerase 2-Alpha
Dna Topoisomerase Ii - Alpha Isozyme
Database Links Reactome: R-MMU-4615885
Cellular Localisation Cytoplasm
Nucleus
Nucleoplasm
Nucleolus
Alternative ELISA Names Dna Topoisomerase 2-Alpha ELISA kit
Dna Topoisomerase Ii - Alpha Isozyme ELISA kit
Top2a ELISA kit
Top-2 ELISA kit
Top2 ELISA kit
output

Information sourced from Uniprot.org

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