Mouse TIMP-1 (Metalloproteinase Inhibitor 1) Antibody Pair (STJAP00267)

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STJAP00267-50
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Host: Rat/Goat
Applications: ELISA
Reactivity: Mouse
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description : This TIMP-1 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA.
Clonality : Monoclonal/Polyclonal
Conjugation: Unconjugated/Biotin
Formulation: Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.
Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.
Purification: Capture Purification: Protein A or G.
Detection Purification: Antigen Affinity.
Concentration: 0.5 mg/mL
Storage Instruction: Store at-20°C for long term, and avoid freeze-thaw cycles.
Gene Symbol: Timp1
Gene ID: 21857
Uniprot ID: TIMP1_MOUSE
Immunogen: Capture immunogen: Recombinant Mouse TIMP-1 protein.
Detection Immunogen: Recombinant Mouse TIMP-1 protein.
Post Translational Modifications The activity of TIMP1 is dependent on the presence of disulfide bonds. N-glycosylated.
Function Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling.
Protein Name Metalloproteinase Inhibitor 1
Collagenase Inhibitor 16c8 Fibroblast
Erythroid-Potentiating Activity
Epa
Tpa-S1
Tpa-Induced Protein
Tissue Inhibitor Of Metalloproteinases 1
Timp-1
Database Links Reactome: R-MMU-114608
Reactome: -MMU-1592389
Reactome: -MMU-381426
Reactome: -MMU-8957275
Reactome: -MMU-9839383
Cellular Localisation Secreted
Alternative Antibody Pair Names Metalloproteinase Inhibitor 1 antibody pair
Collagenase Inhibitor 16c8 Fibroblast antibody pair
Erythroid-Potentiating Activity antibody pair
Epa antibody pair
Tpa-S1 antibody pair
Tpa-Induced Protein antibody pair
Tissue Inhibitor Of Metalloproteinases 1 antibody pair
Timp-1 antibody pair
Timp1 antibody pair
Timp antibody pair
Timp-1 antibody pair

Information sourced from Uniprot.org

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