| Host: |
HEK293 cells |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Mouse Thrombopoietin/THPO-C-6His protein was developed from hek293 cells and has a target region of C-6His. For use in research applications. |
| Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity: |
Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. Avanzi, G. et al. (1988) Br. J. Haematol. 69:359. The ED50 for this effect is 0.45-1.80 ng/mL. |
| Gene Symbol: |
Thpo |
| Gene ID: |
21832 |
| Uniprot ID: |
TPO_MOUSE |
| Immunogen Region: |
Ser22-Thr356 |
| Immunogen: |
Recombinant Mouse Thrombopoietin/THPO Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ser22-Thr356) of mouse Thrombopoietin/THPO (Accession #NP_033405.1.) fused with and a 6×His tag at the C-termi |
| Function | Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets. |
| Protein Name | ThrombopoietinC-Mpl LigandMlMegakaryocyte Colony-Stimulating FactorMegakaryocyte Growth And Development FactorMgdfMyeloproliferative Leukemia Virus Oncogene Ligand |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Thrombopoietin proteinC-Mpl Ligand proteinMl proteinMegakaryocyte Colony-Stimulating Factor proteinMegakaryocyte Growth And Development Factor proteinMgdf proteinMyeloproliferative Leukemia Virus Oncogene Ligand proteinThpo protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
