Function | Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites.an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity. |
Protein Name | SparcBasement-Membrane Protein 40Bm-40OsteonectinOnSecreted Protein Acidic And Rich In Cysteine |
Database Links | Reactome: R-MMU-114608Reactome: -MMU-3000178Reactome: -MMU-3000497 |
Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixBasement MembraneIn Or Around The Basement Membrane |
Alternative Protein Names | Sparc proteinBasement-Membrane Protein 40 proteinBm-40 proteinOsteonectin proteinOn proteinSecreted Protein Acidic And Rich In Cysteine proteinSparc protein |
Information sourced from Uniprot.org