| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | <0.1 EU/Mu g |
| Gene Symbol: | Serpinf1 |
| Gene ID: | 20317 |
| Uniprot ID: | PEDF_MOUSE |
| Immunogen Region: | Gln20-Thr417 |
| Immunogen: | Recombinant Mouse Serpin F1 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln20-Thr417) of mouse Serpin F1 (Accession #NP_035470.3) fused with a 6×His tag at the C-terminus. |
| Immunogen Sequence: | QNVPSSSEGSPVPDSTGEPV EEEDPFFKVPVNKLAAAVSN FGYDLYRLRSSASPTGNVLL SPLSVATALSALSLGAEHRT ESVIHRALYYDLITNPDIHS TYKELLASVTAPEKNLKSAS RIVFERKLRVKSSFVAPLEK SYGTRPRILTGNPRVDLQEI NNWVQAQMKGKIARSTREMP SALSILLLGVAYFKGQWVTK FDSRKTTLQDFHLDEDRTVR VPMMSDPKAILRYGLDSDL |
| Function | Neurotrophic protein.induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. |
| Protein Name | Pigment Epithelium-Derived FactorPedfCaspinSerpin F1Stromal Cell-Derived Factor 3Sdf-3 |
| Cellular Localisation | SecretedMelanosome |
| Alternative Protein Names | Pigment Epithelium-Derived Factor proteinPedf proteinCaspin proteinSerpin F1 proteinStromal Cell-Derived Factor 3 proteinSdf-3 proteinSerpinf1 proteinPedf proteinSdf3 protein |
Information sourced from Uniprot.org
