| Host: | E.coli |
| Applications: | SDS-PAGE/Denatured |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Mouse RAPSN-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol 0.4M urea |
| Concentration: | 0.5 mg/mL |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | Rapsn |
| Gene ID: | 19400 |
| Uniprot ID: | RAPSN_MOUSE |
| Immunogen Region: | 1-412aa |
| Accession Number: | NP_033049 |
| Immunogen: | Mouse |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMGQDQTK QQIEKGLQLY QSNQTEKALQ VWMKVLEKGS DLVGRFRVLG CLVTAHSEMG RYKEMLKFAV VQIDTARGLE DADFLLESYL NLARSNEKLC EFHKTISYCK TCLGLPGTRA GAQLGGQVSL SMGNAFLGLS LFQKALESFE KALRYAHNND DTMLECRVCC SLGSFYAQVK DYEKALFFPC KAAELVNDYG KGWSLKYR |
| Post Translational Modifications | Ubiquitinated by the BCR(KLHL8) complex, leading to its degradation. |
| Function | Postsynaptic protein required for clustering of nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction. It may link the receptor to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. |
| Protein Name | 43 Kda Receptor-Associated Protein Of The SynapseRapsyn43 Kda Postsynaptic ProteinAcetylcholine Receptor-Associated 43 Kda Protein |
| Database Links | |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic SidePostsynaptic Cell MembraneCytoplasmCytoskeletonCytoplasmic Surface Of Postsynaptic Membranes |
| Alternative Protein Names | 43 Kda Receptor-Associated Protein Of The Synapse proteinRapsyn protein43 Kda Postsynaptic Protein proteinAcetylcholine Receptor-Associated 43 Kda Protein proteinRapsn protein |
Information sourced from Uniprot.org