Mouse Nectin-2/PVRL2/CD112 protein (Recombinant) (C-His) (STJP002800)

SKU:
STJP002800

£59.50 - £189.50
Current Stock:
Host: HEK293 cells
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Mouse Nectin-2/PVRL2/CD112-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: Nectin2
Gene ID: 19294
Uniprot ID: NECT2_MOUSE
Immunogen Region: Gln32-Gly351
Immunogen: Recombinant Mouse Nectin-2/PVRL2/CD112 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln32-Gly351) of mouse Nectin-2/PVRL2/CD112 (Accession #NP_033016.3) fused with a 6×His tag at the C-terminus
Function Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive. Probable cell adhesion protein.
Protein Name Nectin-2
Herpes Virus Entry Mediator B
Herpesvirus Entry Mediator B
Hveb
Murine Herpes Virus Entry Protein B
Mhveb
Nectin Cell Adhesion Molecule 2
Poliovirus Receptor Homolog
Poliovirus Receptor-Related Protein 2
Cd Antigen Cd112
Database Links Reactome: R-MMU-198933
Reactome: -MMU-418990
Reactome: -MMU-420597
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Nectin-2 protein
Herpes Virus Entry Mediator B protein
Herpesvirus Entry Mediator B protein
Hveb protein
Murine Herpes Virus Entry Protein B protein
Mhveb protein
Nectin Cell Adhesion Molecule 2 protein
Poliovirus Receptor Homolog protein
Poliovirus Receptor-Related Protein 2 protein
Cd Antigen Cd112 protein
Nectin2 protein
Mph protein
Pvr protein
Pvrl2 protein
Pvs protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance