Function | Phosphatidylserine receptor that plays an important functional role in regulatory B-cells homeostasis including generation, expansion and suppressor functions. As P-selectin/SELPLG ligand, plays a specialized role in activated but not naive T-cell trafficking during inflammatory responses. Controls thereby T-cell accumulation in the inflamed central nervous system (CNS) and the induction of autoimmune disease. Regulates also expression of various anti-inflammatory cytokines and co-inhibitory ligands including IL10. Acts as a regulator of T-cell proliferation. May play a role in kidney injury and repair. |
Protein Name | Hepatitis A Virus Cellular Receptor 1 HomologHavcr-1Kidney Injury Molecule 1Kim-1T Cell Immunoglobulin And Mucin Domain-Containing Protein 1Timd-1T Cell Membrane Protein 1T-Cell Immunoglobulin Mucin Receptor 1Tim-1Cd Antigen Cd365 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
Alternative Antibody Pair Names | Hepatitis A Virus Cellular Receptor 1 Homolog antibody pairHavcr-1 antibody pairKidney Injury Molecule 1 antibody pairKim-1 antibody pairT Cell Immunoglobulin And Mucin Domain-Containing Protein 1 antibody pairTimd-1 antibody pairT Cell Membrane Protein 1 antibody pairT-Cell Immunoglobulin Mucin Receptor 1 antibody pairTim-1 antibody pairCd Antigen Cd365 antibody pairHavcr1 antibody pairKim1 antibody pairTim1 antibody pairTimd1 antibody pair |
Information sourced from Uniprot.org