| Host: | HEK293 |
| Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Mouse Interleukin-18 Binding Protein (IL-18BP)-protein was developed from hek293. For use in research applications. |
| Conjugation: | Unconjugated |
| Formulation: | 0.2 Mu m filtered PBS solution. |
| Dilution Range: | To prepare stock, a quick spin of the vial followed by reconstitution in distilled water to a concentration not less than.1 mg/mL. |
| Storage Instruction: | Can be stored in working aliquots at°C-°C C for one month, or at-20°C C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin: | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than.1 ng/µg (1EU/µg). NA |
| Immunoreactivity: | The activity of recombinant Interleukin-18 Binding Protein was determined by the ability to bind IL-18 in functional ELISA. NA |
| Gene Symbol: | Il18bp |
| Gene ID: | 16068 |
| Uniprot ID: | I18BP_MOUSE |
| Immunogen Region: | Mature chain |
| Immunogen: | Optimized DNA sequence encoding Mouse Interleukin-18 Binding Protein (IL-18BP) mature chain fused to an C-terminal polyHis tag was expressed in HEK cells. NA |
| Immunogen Sequence: | MTMRHCWTAG PSSWWVLLLY VHVILARATS APQTTATVLT GSSKDPCSSW SPAVPTKQYP ALDVIWPEKE VPLNGTLTLS CTACSRFPYF SILYWLGNGS FIEHLPGRLK EGHTSREHRN TSTWLHRALV LEELSPTLRS TNFSCLFVDP GQVAQYHIIL AQLWDGLKTA PSPSQETLSS HSPVSRSAGP GVA NA |
| Function | Binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response. |
| Protein Name | Interleukin-18-Binding ProteinIl-18bpInterferon Gamma-Inducing Factor-Binding Protein |
| Database Links | Reactome: R-MMU-9012546 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Interleukin-18-Binding Protein proteinIl-18bp proteinInterferon Gamma-Inducing Factor-Binding Protein proteinIl18bp proteinIgifbp protein |
Information sourced from Uniprot.org
