Mouse IL-5 (Interleukin-5) Antibody Pair (STJAP00537)

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STJAP00537-50
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Host: Rat/Rat
Applications: ELISA
Reactivity: Mouse
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description : This IL-5 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA.
Conjugation: Unconjugated/Biotin
Formulation: Capture Buffer: PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5.
Detection Buffer: PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5.
Purification: Capture Purification: Protein A or G.
Detection Purification: Protein A or G.
Concentration: 0.5 mg/mL
Storage Instruction: Store at-20°C for long term, and avoid freeze-thaw cycles.
Determination Method: Colormetric
Gene Symbol: Il5
Gene ID: 16191
Uniprot ID: IL5_MOUSE
Immunogen: Capture immunogen: Recombinant Mouse IL-5 protien.
Detection Immunogen: Recombinant Mouse IL-5 protien.
Sample Type: Serum, plasma and other biological fluids
Function Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Acts also on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation. Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB. Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively.
Protein Name Interleukin-5
Il-5
B-Cell Growth Factor Ii
Bcgf-Ii
Cytotoxic T-Lymphocyte Inducer
Eosinophil Differentiation Factor
T-Cell Replacing Factor
Trf
Database Links Reactome: R-MMU-512988
Reactome: -MMU-5673001
Reactome: -MMU-912526
Cellular Localisation Secreted
Alternative Antibody Pair Names Interleukin-5 antibody pair
Il-5 antibody pair
B-Cell Growth Factor Ii antibody pair
Bcgf-Ii antibody pair
Cytotoxic T-Lymphocyte Inducer antibody pair
Eosinophil Differentiation Factor antibody pair
T-Cell Replacing Factor antibody pair
Trf antibody pair
Il5 antibody pair
Il-5 antibody pair

Information sourced from Uniprot.org

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