| Host: |
Rat/Goat |
| Applications: |
ELISA |
| Reactivity: |
Mouse |
| Note: |
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description: |
This ICAM-1/CD54 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Conjugation: |
Unconjugated/Biotin |
| Formulation: |
Capture Buffer: PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5.Detection Buffer: PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5. |
| Purification: |
Capture Purification: Protein A or G.Detection Purification: Antigen Affinity. |
| Concentration: |
0.5 mg/mL |
| Storage Instruction: |
Store at-20°C for long term, and avoid freeze-thaw cycles. |
| Determination Method: |
Colormetric |
| Gene Symbol: |
Icam1 |
| Gene ID: |
15894 |
| Uniprot ID: |
ICAM1_MOUSE |
| Immunogen: |
Capture immunogen: Recombinant Mouse ICAM-1/CD54 protien.Detection Immunogen: Recombinant Mouse ICAM-1/CD54 protien. |
| Sample Type: |
Serum, plasma and other biological fluids |
| Post Translational Modifications | Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis. |
| Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. |
| Protein Name | Intercellular Adhesion Molecule 1Icam-1Mala-2Myd10Cd Antigen Cd54 |
| Database Links | Reactome: R-MMU-198933Reactome: -MMU-216083 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Pair Names | Intercellular Adhesion Molecule 1 antibody pairIcam-1 antibody pairMala-2 antibody pairMyd10 antibody pairCd Antigen Cd54 antibody pairIcam1 antibody pairIcam-1 antibody pair |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
