Mouse Glutathione S-transferase A1/GSTA1 protein (Recombinant) (His-Tag) (STJP019162)

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STJP019162
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Host: E.coli
Applications: SDS-PAGE/Enzyme Activity
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Mouse Glutathione S-transferase A1/GSTA1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol, 1mM DTT
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Immunoreactivity: Specific activity is > 4, 000pmol/min/ug, and is defined as the amount of enzyme that conjugate 1.0pmole of 1-chloro-2, 4-dinitrobenzene (CDNB) with reduced glutathione per minute at pH 6.5 at 25C.
Gene Symbol: Gsta1
Gene ID: 14857
Uniprot ID: GSTA1_MOUSE
Immunogen Region: 1-223aa
Accession Number: NP_032207
Immunogen: Mouse
Immunogen Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAGKPVL HYFNARGRME CIRWLLAAAG VEFEEKFIQS PEDLEKLKKD GNLMFDQVPM VEIDGMKLAQ TRAILNYIAT KYDLYGKDMK ERALIDMYSE GILDLTEMIG QLVLCPPDQR EAKTALAKDR TKNRYLPAFE KVLKSHGQDY LVGNRLTRVD IHLLEVLLYV EEFDASLLTP FPLLKAFKSR ISSLPNVKKF LQPGSQRK
Tissue Specificity Expressed in the liver, skin and kidney.
Function Glutathione S-transferase that catalyzes the nucleophilic attack of the sulfur atom of glutathione on the electrophilic groups of a wide range of exogenous and endogenous compounds. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). It also catalyzes the isomerization of D5-androstene-3,17-dione (AD) into D4-androstene-3,17-dione and may therefore play an important role in hormone biosynthesis. Through its glutathione-dependent peroxidase activity toward the fatty acid hydroperoxide (13S)-hydroperoxy-(9Z,11E)-octadecadienoate/13-HPODE it is also involved in the metabolism of oxidized linoleic acid.
Protein Name Glutathione S-Transferase A1
13-Hydroperoxyoctadecadienoate Peroxidase
Androst-5-Ene-3 -17-Dione Isomerase
Gst Class-Alpha Member 1
Glutathione S-Transferase Ya
Glutathione S-Transferase Ya1 Cleaved Into - Glutathione S-Transferase A1 - N-Terminally Processed
Database Links Reactome: R-MMU-156590
Reactome: -MMU-189483
Reactome: -MMU-9748787
Cellular Localisation
Alternative Protein Names Glutathione S-Transferase A1 protein
13-Hydroperoxyoctadecadienoate Peroxidase protein
Androst-5-Ene-3 -17-Dione Isomerase protein
Gst Class-Alpha Member 1 protein
Glutathione S-Transferase Ya protein
Glutathione S-Transferase Ya1 Cleaved Into - Glutathione S-Transferase A1 - N-Terminally Processed protein
Gsta1 protein
Gsta protein
Gstya protein

Information sourced from Uniprot.org

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