Mouse Glutathione S-Transferase Pi 1/GSTP1 protein (Recombinant) (His-Tag) (STJP019207)
SPECIFICATIONS
HostE.coli
ImmunogenMouse
General Information
| Short Description | Recombinant-Mouse Glutathione S-Transferase Pi 1/GSTP1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Enzyme Activity |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | Specific activity is > 40unit/mg, and is defined as the amount of enzyme that conjugate 1.0 umole of 1-chloro-2, 4-dinitrobenzene (CDNB) with reduced glutathione per minute at pH 6.5 at 25C. |
Target Information
| Gene Symbol | Gstp1 |
| Gene ID | 14870 |
| Uniprot ID | GSTP1_MOUSE |
| Accession Number | NP_038569 |
| Immunogen | Mouse |
| Immunogen Region | 1-210aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Ubiquitously expressed. |
| Function | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers. Negatively regulates CDK5 activity via p25/p35 translocation to prevent neurodegeneration. |
| Protein Name | Glutathione S-Transferase P 1Gst P1Gst Yf-YfGst Class-PiGst-PibPreadipocyte Growth Factor |
| Database Links | Reactome: R-MMU-156590Reactome: -MMU-3299685Reactome: -MMU-6798695Reactome: -MMU-9753281 |
| Cellular Localisation | CytoplasmMitochondrionNucleusThe 83 N-Terminal Amino Acids Function As Un Uncleaved Transit PeptideAnd Arginine Residues Within It Are Crucial For Mitochondrial Localization |
| Alternative Protein Names | Glutathione S-Transferase P 1 proteinGst P1 proteinGst Yf-Yf proteinGst Class-Pi proteinGst-Pib proteinPreadipocyte Growth Factor proteinGstp1 proteinGstpib protein |
Information sourced from Uniprot.org