| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from a 0.2 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity: | Measured in a cell proliferation assay using NFS-60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is 38.7-154.8 pg/mL, corresponding to a specific activity of 6.46×106-2.58×107 units/mg. |
| Determination Method: | < 1 EU/Mu g of the protein by LAL method. |
| Gene Symbol: | Csf3 |
| Gene ID: | 12985 |
| Uniprot ID: | CSF3_MOUSE |
| Immunogen: | Recombinant Mouse G-CSF/CSF3 Protein is produced by Human Cells expression system. The target protein is expressed with sequence (Met1-Ala208) of mouse G-CSF/CSF3 (Accession #P09920) fused with a 6×His tag at the C-terminus. |
| Immunogen Region: | Met1-Ala208 |
| Immunogen Sequence: | VPLVTVSALPPSLPLPRSFL LKSLEQVRKIQASGSVLLEQ LCATYKLCHPEELVLLGHSL GIPKASLSGCSSQALQQTQC LSQLHSGLCLYQGLLQALSG ISPALAPTLDLLQLDVANFA TTIWQQMENLGVAPTVQPTQ SAMPAFTSAFQRRAGGVLAI SYLQGFLETARLALHHLA |
| Function | Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes. |
| Protein Name | Granulocyte Colony-Stimulating FactorG-Csf |
| Database Links | Reactome: R-MMU-9674555Reactome: -MMU-9705462 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Granulocyte Colony-Stimulating Factor proteinG-Csf proteinCsf3 proteinCsfg protein |
Information sourced from Uniprot.org
