| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 1 EU/Mu g of the protein by LAL method. |
| Gene Symbol: | Fshb |
| Gene ID: | 14308 |
| Uniprot ID: | FSHB_MOUSE |
| Immunogen Region: | His20-Glu130 |
| Immunogen: | Recombinant Mouse FSH Beta Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (His20-Glu130) of mouse FSH Beta (Accession #NP_032071.1) fused with a hFc tag at the C-terminus. |
| Immunogen Sequence: | HSCELTNITISVEKEECRFC ISINTTWCAGYCYTRDLVYK DPARPNTQKVCTFKELVYET VRLPGCARHSDSLYTYPVAT ECHCGKCDSDSTDCTVRGLG PSYCSFSEMKE |
| Function | Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. |
| Protein Name | Follitropin Subunit BetaFollicle-Stimulating Hormone Beta SubunitFsh-BFsh-BetaFollitropin Beta Chain |
| Database Links | Reactome: R-MMU-209822Reactome: -MMU-375281Reactome: -MMU-418555 |
| Cellular Localisation | SecretedEfficient Secretion Requires Dimerization With Cga |
| Alternative Protein Names | Follitropin Subunit Beta proteinFollicle-Stimulating Hormone Beta Subunit proteinFsh-B proteinFsh-Beta proteinFollitropin Beta Chain proteinFshb protein |
Information sourced from Uniprot.org
