Mouse Flt3 ligand/Flt3L protein (Recombinant) (C-hFc&His) (STJP001138)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenActive Recombinant Mouse Flt3 ligand/Flt3L Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Met1-Arg188) of mouse Flt-3 Ligand (Accession #NP_038548.3.) fused with an Fc, 6×His tag at the C-terminus.
General Information
| Short Description | Recombinant-Mouse Flt3 ligand/Flt3L-C-hFc&His protein was developed in hek293 cells using the region Met1-Arg188. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | Measured by its binding ability in a functional ELISA. Immobilized Recombinant Mouse FLT3, His Tag at 3 Mu g/mL (100 Mu L/well) can bind Recombinant Mouse Flt-3 Ligand, The EC50 of Mouse Flt-3 Ligand is 36 ng/mL. |
| Determination Method | < 0.1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | Flt3lg |
| Gene ID | 14256 |
| Uniprot ID | FLT3L_MOUSE |
| Immunogen | Active Recombinant Mouse Flt3 ligand/Flt3L Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Met1-Arg188) of mouse Flt-3 Ligand (Accession #NP_038548.3.) fused with an Fc, 6×His tag at the C-terminus. |
| Immunogen Region | Met1-Arg188 |
| Immunogen Sequence | MTVLAPAWSPNSSLLLLLLL LSPCLRGTPDCYFSHSPISS NFKVKFRELTDHLLKDYPVT VAVNLQDEKHCKALWSLFLA QRWIEQLKTVAGSKMQTLLE DVNTEIHFVTSCTFQPLPEC LRFVQTNISHLLKDTCTQLL ALKPCIGKACQNFSRCLEVQ CQPDSSTLLPPRSPIALEAT ELPEPRPR |
Additional Info
| Protein Name | Fms-Related Tyrosine Kinase 3 LigandFlt3 LigandFlt3lSl Cytokine |
| Database Links | Reactome: R-MMU-109704Reactome: -MMU-1257604Reactome: -MMU-5673001Reactome: -MMU-6811558Reactome: -MMU-9607240Reactome: -MMU-9706369Reactome: -MMU-9706374 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 3: SecretedBiologically ActiveIsoform 4: SecretedInactive |
| Alternative Protein Names | Fms-Related Tyrosine Kinase 3 Ligand proteinFlt3 Ligand proteinFlt3l proteinSl Cytokine proteinFlt3lg proteinFlt3l protein |
Information sourced from Uniprot.org