Mouse FLG (Filaggrin) Sandwich ELISA Kit Ready-To-Use Kit (STJE0015318)
SPECIFICATIONS
General Information
| Short Description | This FLG Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Mouse |
| Sensitivity | 0.136ng/mL |
| Detection Limit | 0.312-20ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | FlgUniprot ID=FILA_MOUSE" |
| Immunogen Region | Ready-To-Use |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | Expressed in the granular layer of the epidermis (at protein level). Expressed in the epidermis of the ear (at protein level). |
| Post Translational Modifications | Filaggrin is initially synthesized as a large, insoluble, highly phosphorylated precursor containing many tandem copies of 248 AA, which are not separated by large linker sequences. During terminal differentiation it is dephosphorylated and proteolytically cleaved. |
| Function | Aggregates keratin intermediate filaments and promotes disulfide-bond formation among the intermediate filaments during terminal differentiation of mammalian epidermis. |
| Protein Name | Filaggrin |
| Database Links | |
| Cellular Localisation | Cytoplasmic GranuleIn The Stratum Granulosum Of The EpidermisLocalized Within Keratohyalin GranulesIn Granular Keratinocytes And In Lower CorneocytesColocalizes With Calpain-1/Capn1 |
| Alternative ELISA Names | Filaggrin ELISA kitFlg ELISA kit |
| output |
Information sourced from Uniprot.org