Mouse FLG (Filaggrin) Sandwich ELISA Kit Ready-To-Use Kit (STJE0015318)

Mouse FLG (Filaggrin) Sandwich ELISA Kit Ready-To-Use Kit (STJE0015318)

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STJE0015318
£496.50 - £681.50
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Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.136ng/mL
Detection Limit: 0.312-20ng/mL
Short Description : This FLG Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse tissue homogenates, cell lysates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Flg
Uniprot ID: FILA_MOUSE
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Expressed in the granular layer of the epidermis (at protein level). Expressed in the epidermis of the ear (at protein level).
Post Translational Modifications Filaggrin is initially synthesized as a large, insoluble, highly phosphorylated precursor containing many tandem copies of 248 AA, which are not separated by large linker sequences. During terminal differentiation it is dephosphorylated and proteolytically cleaved.
Function Aggregates keratin intermediate filaments and promotes disulfide-bond formation among the intermediate filaments during terminal differentiation of mammalian epidermis.
Protein Name Filaggrin
Database Links
Cellular Localisation Cytoplasmic Granule
In The Stratum Granulosum Of The Epidermis
Localized Within Keratohyalin Granules
In Granular Keratinocytes And In Lower Corneocytes
Colocalizes With Calpain-1/Capn1
Alternative ELISA Names Filaggrin ELISA kit
Flg ELISA kit
output

Information sourced from Uniprot.org

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