Mouse FKBP12/FKBP1A protein (Recombinant) (His-Tag) (STJP019160)

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STJP019160
£134.50 - £738.50
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Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Mouse FKBP12/FKBP1A-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in phosphate-Buffered Saline (pH 7.4) containing 20% Glycerol, 1mM DTT
Concentration: 0.5 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: Fkbp1a
Gene ID: 14225
Uniprot ID: FKB1A_MOUSE
Immunogen Region: 1-108aa
Accession Number: NP_032045
Immunogen: Mouse
Immunogen Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMGVQVE TISPGDGRTF PKRGQTCVVH YTGMLEDGKK FDSSRDRNKP FKFTLGKQEV IRGWEEGVAQ MSVGQRAKLI ISSDYAYGAT GHPGIIPPHA TLVFDVELLK LE
Function Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruits SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Protein Name Peptidyl-Prolyl Cis-Trans Isomerase Fkbp1a
Ppiase Fkbp1a
12 Kda Fk506-Binding Protein
12 Kda Fkbp
Fkbp-12
Calstabin-1
Fk506-Binding Protein 1a
Fkbp-1a
Immunophilin Fkbp12
Rotamase
Database Links Reactome: R-MMU-166208
Reactome: -MMU-2025928
Reactome: -MMU-2173789
Cellular Localisation Cytoplasm
Cytosol
Sarcoplasmic Reticulum Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Alternative Protein Names Peptidyl-Prolyl Cis-Trans Isomerase Fkbp1a protein
Ppiase Fkbp1a protein
12 Kda Fk506-Binding Protein protein
12 Kda Fkbp protein
Fkbp-12 protein
Calstabin-1 protein
Fk506-Binding Protein 1a protein
Fkbp-1a protein
Immunophilin Fkbp12 protein
Rotamase protein
Fkbp1a protein
Fkbp1 protein

Information sourced from Uniprot.org

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