Mouse EGFLAM protein (Recombinant) (N-His) (STJP009139)

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STJP009139
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Mouse EGFLAM-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: Egflam
Gene ID: 268780
Uniprot ID: EGFLA_MOUSE
Immunogen Region: Asp40-Thr236
Immunogen: Mus musculus (Mouse)
Post Translational Modifications O-glycosylated.contains chondroitin sulfate and heparan sulfate.
Function Involved in both the retinal photoreceptor ribbon synapse formation and physiological functions of visual perception. Plays a key role in the synaptic organization of photoreceptors by mediating transsynaptic interaction between alpha-dystroglycan and GPR179 on the postsynaptic membrane. Necessary for proper bipolar dendritic tip apposition to the photoreceptor ribbon synapse. Promotes matrix assembly and cell adhesiveness.
Protein Name Pikachurin
Egf-Like - Fibronectin Type-Iii And Laminin G-Like Domain-Containing Protein
Nectican
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Synaptic Cleft
Presynaptic Active Zone
Detected In The Synaptic Cleft Of The Ribbon Synapse Around The Postsynaptic Terminals Of Bipolar Cells
Colocalizes With Bsn
Ctbp2 And Dag1 In Photoreceptor Synaptic Terminals
Alternative Protein Names Pikachurin protein
Egf-Like - Fibronectin Type-Iii And Laminin G-Like Domain-Containing Protein protein
Nectican protein
Egflam protein

Information sourced from Uniprot.org

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