Mouse EGFLAM protein (Recombinant) (N-His) (STJP009139)

SPECIFICATIONS
HostE.coli
ImmunogenMus musculus (Mouse)
STJP009139
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General Information

Short DescriptionRecombinant-Mouse EGFLAM-N-His protein was developed from e.coli for the region N-His. For use in research applications.
ApplicationsELISA/Immunogen/SDS-PAGE/WB
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Dilution RangeReconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
FormulationLyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Target Information

Gene SymbolEgflam
Gene ID268780
Uniprot IDEGFLA_MOUSE
ImmunogenMus musculus (Mouse)
Immunogen RegionAsp40-Thr236

Additional Info

Post Translational Modifications O-glycosylated.contains chondroitin sulfate and heparan sulfate.
Function Involved in both the retinal photoreceptor ribbon synapse formation and physiological functions of visual perception. Plays a key role in the synaptic organization of photoreceptors by mediating transsynaptic interaction between alpha-dystroglycan and GPR179 on the postsynaptic membrane. Necessary for proper bipolar dendritic tip apposition to the photoreceptor ribbon synapse. Promotes matrix assembly and cell adhesiveness.
Protein Name Pikachurin
Egf-Like - Fibronectin Type-Iii And Laminin G-Like Domain-Containing Protein
Nectican
Database Links
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Synaptic Cleft
Presynaptic Active Zone
Detected In The Synaptic Cleft Of The Ribbon Synapse Around The Postsynaptic Terminals Of Bipolar Cells
Colocalizes With Bsn
Ctbp2 And Dag1 In Photoreceptor Synaptic Terminals
Alternative Protein Names Pikachurin protein
Egf-Like - Fibronectin Type-Iii And Laminin G-Like Domain-Containing Protein protein
Nectican protein
Egflam protein

Information sourced from Uniprot.org

Citations

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