| Applications: | ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.051ng/mL |
| Detection Limit: | 0.156-10ng/mL |
| Short Description : | This DSC1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse tissue homogenates, cell lysates or other biological fluids. |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
| Gene Symbol: | Dsc1 |
| Gene ID: | 13505 |
| Uniprot ID: | DSC1_MOUSE |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | Expressed in the epidermis and inner root sheaths of hair follicles (at protein level). |
| Post Translational Modifications | |
| Function | A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion. Required for desmosome adhesion strength between the granular layers of the epidermis, as a result moderates epidermal proliferation and differentiation. Is therefore required to maintain postnatal epidermal barrier function and normal hair follicle morphology into adulthood. |
| Protein Name | Desmocollin-1 |
| Database Links | Reactome: R-MMU-6798695Reactome: -MMU-6805567Reactome: -MMU-6809371 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCell JunctionDesmosome |
| Alternative ELISA Names | Desmocollin-1 ELISA kitDsc1 ELISA kit |
| output |
Information sourced from Uniprot.org
