Human DSC3 (Desmocollin 3) Sandwich ELISA Kit Ready-To-Use Kit (STJE0014893)
SPECIFICATIONS
General Information
| Short Description | This DSC3 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.062ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | DSC3 |
| Gene ID | 1825 |
| Uniprot ID | DSC3_HUMAN |
| Immunogen Region | Ready-To-Use |
| Sample Type | serum, plasma, tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | Expressed throughout the basal and spinous layer of the epidermis with weak expression in the granular layer (at protein level). Also expressed in the buccal mucosa, esophagus and cervix (at protein level). |
| Post Translational Modifications | |
| Function | A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion. Required for cell-cell adhesion in the epidermis, as a result required for the maintenance of the dermal cohesion and the dermal barrier function. Required for cell-cell adhesion of epithelial cell layers surrounding the telogen hair club, as a result plays an important role in telogen hair shaft anchorage. Essential for successful completion of embryo compaction and embryo development. |
| Protein Name | Desmocollin-3Cadherin Family Member 3Desmocollin-4Ht-Cp |
| Database Links | Reactome: R-HSA-6805567Reactome: R-HSA-6809371 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCell JunctionDesmosomeCytoplasmExpressed In The Cytoplasm And At The Cell Membrane Of Oocytes |
| Alternative ELISA Names | Desmocollin-3 ELISA kitCadherin Family Member 3 ELISA kitDesmocollin-4 ELISA kitHt-Cp ELISA kitDSC3 ELISA kitCDHF3 ELISA kitDSC4 ELISA kit |
| output |
Information sourced from Uniprot.org