| Short Description : | Recombinant-Mouse CXCL16/SR-PSOX-C-His protein was developed in hek293 cells using the region Asn27-Trp201. For use in research applications. |
| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 0.1 EU/Mu g of the protein by LAL method. |
| Gene Symbol: | Cxcl16 |
| Gene ID: | 66102 |
| Uniprot ID: | CXL16_MOUSE |
| Immunogen: | Recombinant Mouse CXCL16/SR-PSOX Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Asn27-Trp201) of mouse CXCL16 (Accession #NP_075647.3) fused with a 6×His tag at the C-terminus. |
| Immunogen Region: | Asn27-Trp201 |
| Immunogen Sequence: | NQGSVAGSCSCDRTISSGTQ IPQGTLDHIRKYLKAFHRCP FFIRFQLQSKSVCGGSQDQW VRELVDCFERKECGTGHGKS FHHQKHLPQASTQTPEAAEG TPSDTSTPAHSQSTQHSTLP SGALSLNKEHTQPWEMTTLP SGYGLEARPEAEANEKQQDD RQQEAPGAGASTPAW |
| Post Translational Modifications | Glycosylated. |
| Function | Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo. Also acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis. |
| Protein Name | C-X-C Motif Chemokine 16Scavenger Receptor For Phosphatidylserine And Oxidized Low Density LipoproteinSr-PsoxSmall-Inducible Cytokine B16Transmembrane Chemokine Cxcl16 |
| Database Links | Reactome: R-MMU-380108Reactome: -MMU-418594 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | C-X-C Motif Chemokine 16 proteinScavenger Receptor For Phosphatidylserine And Oxidized Low Density LipoproteinSr-Psox proteinSmall-Inducible Cytokine B16 proteinTransmembrane Chemokine Cxcl16 proteinCxcl16 proteinSrpsox protein |
Information sourced from Uniprot.org
