Host: | Pichia |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Determination Method: | <0.1 EU/Mu g |
Immunoreactivity: | Measured by its binding ability in a functional ELISA. Immobilized Mouse CXCL1 at 2 Mu g/mL (100 Mu L/well) can bind GRO alpha Rabbit pAb with a linear range of 0.6-2.37 ng/mL. |
Gene Symbol: | Cxcl1 |
Gene ID: | 14825 |
Uniprot ID: | GROA_MOUSE |
Immunogen Region: | Arg20-Lys96 |
Immunogen: | Recombinant Mouse CXCL1/GRO-alpha Protein is produced by Pichia expression system. The target protein is expressed with sequence (Arg20-Lys96) of mouse CXCL1/GRO-alpha (Accession #NP_032202.1) fused with no additional amino acid. |
Immunogen Sequence: | RLATGAPIANELRCQCLQTM AGIHLKNIQSLKVLPSGPHC TQTEVIATLKNGREACLDPE APLVQKIVQKMLKGVPK |
Function | Has chemotactic activity for neutrophils. Contributes to neutrophil activation during inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. KC(5-72) shows a highly enhanced hematopoietic activity. |
Protein Name | Growth-Regulated Alpha ProteinC-X-C Motif Chemokine 1Platelet-Derived Growth Factor-Inducible Protein KcSecretory Protein N51 Cleaved Into - Kc(5-72Hematopoietic Synergistic FactorHsfKc-T |
Database Links | Reactome: R-MMU-380108Reactome: -MMU-418594Reactome: -MMU-6798695 |
Cellular Localisation | Secreted |
Alternative Protein Names | Growth-Regulated Alpha Protein proteinC-X-C Motif Chemokine 1 proteinPlatelet-Derived Growth Factor-Inducible Protein Kc proteinSecretory Protein N51 Cleaved Into - Kc(5-72 proteinHematopoietic Synergistic Factor proteinHsf proteinKc-T proteinCxcl1 proteinGro proteinGro1 proteinMgsa proteinScyb1 protein |
Information sourced from Uniprot.org