Mouse CTSB protein (Recombinant-Active) (C-10*His) (STJP011846)

Name: Mouse CTSB protein (Recombinant-Active) (C-10*His) (STJP011846)
SKU: STJP011846-100
Price: 604.2 EUR
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostMammalian Cells

ConjugationUnconjugated

ImmunogenMus musculus (Mouse)

STJP011846-100

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Short Description	Recombinant-Active-Mouse CTSB-C-10His protein was developed from mammalian cells and has a target region of C-10His. For use in research applications.
Applications	ELISA/WB
Host	Mammalian Cells
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Conjugation	Unconjugated
Dilution Range	Reconstitute in sterile water for a stock solution.
Formulation	Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin	<0.1 EU/Mu g of the protein by the LAL method.
Immunoreactivity	Measured by its ability to cleave the fluorogenic peptide substrate Z-LR-AMC. The specific activity is >2, 000 pmol/min/µg, as measured under the described conditions.

Function	Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Cleaves matrix extracellular phosphoglycoprotein MEPE. Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen. Has also been implicated in tumor invasion and metastasis.
Protein Name	Cathepsin B Cathepsin B1 Cleaved Into - Cathepsin B Light Chain - Cathepsin B Heavy Chain
Database Links	Reactome: R-MMU-1442490 Reactome: -MMU-1679131 Reactome: -MMU-2022090 Reactome: -MMU-2132295 Reactome: -MMU-6798695
Cellular Localisation	Lysosome Melanosome Secreted Extracellular Space Apical Cell Membrane Peripheral Membrane Protein Extracellular Side Localizes To The Lumen Of Thyroid Follicles And To The Apical Membrane Of Thyroid Epithelial Cells
Alternative Protein Names	Cathepsin B protein Cathepsin B1 Cleaved Into - Cathepsin B Light Chain - Cathepsin B Heavy Chain protein Ctsb protein

Information sourced from Uniprot.org