Host: | Mammalian Cells |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Recombinant-Mouse CD276/B7-H3-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
Formulation: | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Gene Symbol: | Cd276 |
Gene ID: | 102657 |
Uniprot ID: | CD276_MOUSE |
Immunogen Region: | Ala28-Phe244 |
Immunogen: | Mus musculus (Mouse) |
Function | Modulates T-cell-mediated immune responses and the development of acute and chronic transplant rejection. Plays a positive regulatory role in bone formation and has a dual role in the bone-immune interface. Induces antitumor immunity as it activates both acquired and innate immunity leading to natural killer cell and CD8 T-cell dependent killing of tumor cells. |
Protein Name | Cd276 AntigenB7 Homolog 3B7-H3Costimulatory MoleculeCd Antigen Cd276 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
Alternative Protein Names | Cd276 Antigen proteinB7 Homolog 3 proteinB7-H3 proteinCostimulatory Molecule proteinCd Antigen Cd276 proteinCd276 proteinB7h3 protein |
Information sourced from Uniprot.org