| Function | Modulates T-cell-mediated immune responses and the development of acute and chronic transplant rejection. Plays a positive regulatory role in bone formation and has a dual role in the bone-immune interface. Induces antitumor immunity as it activates both acquired and innate immunity leading to natural killer cell and CD8 T-cell dependent killing of tumor cells. |
| Protein Name | Cd276 AntigenB7 Homolog 3B7-H3Costimulatory MoleculeCd Antigen Cd276 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Cd276 Antigen proteinB7 Homolog 3 proteinB7-H3 proteinCostimulatory Molecule proteinCd Antigen Cd276 proteinCd276 proteinB7h3 protein |
Information sourced from Uniprot.org