Mouse CD125/IL5RA protein (Recombinant) (N-His) (STJP009796)

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STJP009796
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Mouse CD125/IL5RA-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: Il5ra
Gene ID: 16192
Uniprot ID: IL5RA_MOUSE
Immunogen Region: Asn32-Gly329
Immunogen: Mus musculus (Mouse)
Function Cell surface receptor that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Acts by forming a heterodimeric receptor with CSF2RB subunit and subsequently binding to interleukin-5. In unstimulated conditions, interacts constitutively with JAK2. Heterodimeric receptor activation leads to JAK2 stimulation and subsequent activation of the JAK-STAT pathway.
Protein Name Interleukin-5 Receptor Subunit Alpha
Il-5 Receptor Subunit Alpha
Il-5r Subunit Alpha
Il-5r-Alpha
Il-5ra
Cd Antigen Cd125
Database Links Reactome: R-MMU-512988
Reactome: -MMU-5673001
Reactome: -MMU-912526
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Interleukin-5 Receptor Subunit Alpha protein
Il-5 Receptor Subunit Alpha protein
Il-5r Subunit Alpha protein
Il-5r-Alpha protein
Il-5ra protein
Cd Antigen Cd125 protein
Il5ra protein
Il5r protein

Information sourced from Uniprot.org

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