| Host: | Mammalian Cells |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Mouse CD120a/TNFRSF1A/TNFR1-C-Fc protein was developed from mammalian cells and has a target region of C-Fc. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | Tnfrsf1a |
| Gene ID: | 21937 |
| Uniprot ID: | TNR1A_MOUSE |
| Immunogen Region: | Met1-Ala212 |
| Immunogen: | Mus musculus (Mouse) |
| Function | Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 1aTumor Necrosis Factor Receptor 1Tnf-R1Tumor Necrosis Factor Receptor Type ITnf-RiTnfr-IP55P60Cd Antigen Cd120a |
| Database Links | Reactome: R-MMU-5357786Reactome: -MMU-5357905Reactome: -MMU-5357956Reactome: -MMU-5626978Reactome: -MMU-5669034Reactome: -MMU-75893 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinGolgi Apparatus Membrane |
| Alternative Protein Names | Tumor Necrosis Factor Receptor Superfamily Member 1a proteinTumor Necrosis Factor Receptor 1 proteinTnf-R1 proteinTumor Necrosis Factor Receptor Type I proteinTnf-Ri proteinTnfr-I proteinP55 proteinP60 proteinCd Antigen Cd120a proteinTnfrsf1a proteinTnfr-1 proteinTnfr1 protein |
Information sourced from Uniprot.org
![Anti-CD120a/TNFRSF1A/TNFR1 nanobody [SAA1242] (STJN000167)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/200780/412962/STJN000167-SDS-PAGE-1__76805.1749232490.jpg?c=1 "Anti-CD120a/TNFRSF1A/TNFR1 nanobody [SAA1242] (STJN000167)")