| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | <1 EU/Mu g |
| Gene Symbol: | Ccl6 |
| Gene ID: | 20305 |
| Uniprot ID: | CCL6_MOUSE |
| Immunogen Region: | Gly22-Ala116 |
| Immunogen: | Recombinant Mouse CCL6 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly22-Ala116) of mouse CCL6 (Accession #NP_033165.1.) fused with and a 6×His tag at the C-terminus. |
| Immunogen Sequence: | GLIQEMEKEDRRYNPPIIHQ GFQDTSSDCCFSYATQIPCK RFIYYFPTSGGCIKPGIIFI SRRGTQVCADPSDRRVQRCL STLKQGPRSGNKVIA |
| Post Translational Modifications | The N-terminal is proteolytically cleaved by proteases associated with inflammatory responses. The processed forms CL6(22-95) and CCL6(23-95) show increase in CCR1-mediated signaling and chemotaxis assays in vitro. |
| Function | Chemotactic factor that attracts mostly macrophage, but it can also attract B cells, CD4(+) lymphocytes and eosinophils. |
| Protein Name | C-C Motif Chemokine 6Protein C10Small-Inducible Cytokine A6 Cleaved Into - Ccl6(22-95 - Ccl6(23-95 |
| Database Links | Reactome: R-MMU-416476Reactome: -MMU-418594Reactome: -MMU-444473 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | C-C Motif Chemokine 6 proteinProtein C10 proteinSmall-Inducible Cytokine A6 Cleaved Into - Ccl6(22-95 - Ccl6(23-95 proteinCcl6 proteinC10 proteinScya6 protein |
Information sourced from Uniprot.org
