Mouse Cathepsin S/CTSS protein (Recombinant) (C-His) (STJP002816)

SKU:
STJP002816

Current Stock:
Host: HEK293 cells
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Mouse Cathepsin S/CTSS-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Immunoreactivity: Measured by its ability to cleave the fluorogenic peptide substrate, Mca-RPKPVE-Nval-WRK (Dnp)-NH2 (RD, Catalog # ES002). The specific activity is >212 pmol/min/Mu g, as measured under the described conditions.
Gene Symbol: Ctss
Gene ID: 13040
Uniprot ID: CATS_MOUSE
Immunogen Region: Val18-Ile340
Immunogen: Recombinant Mouse Cathepsin S/CTSS Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val18-Ile340) of mouse Cathepsin S/CTSS (Accession #NP_067256.4) fused with and a 6×His tag at the C-terminus.
Function Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules and MHC class II antigen presentation. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L.
Protein Name Cathepsin S
Database Links Reactome: R-MMU-1474228
Reactome: -MMU-1679131
Reactome: -MMU-2022090
Reactome: -MMU-2132295
Reactome: -MMU-6798695
Cellular Localisation Lysosome
Secreted
Cytoplasmic Vesicle
Phagosome
Alternative Protein Names Cathepsin S protein
Ctss protein
Cats protein

Information sourced from Uniprot.org

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