Mouse Cathepsin S/CTSS protein (Recombinant) (C-His) (STJP002816)

SKU:
STJP002816

Current Stock:
Host: HEK293 cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Formulation: Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: < 0.1 EU/Mu g of the protein by LAL method.
Immunoreactivity: Measured by its ability to cleave the fluorogenic peptide substrate, Mca-RPKPVE-Nval-WRK (Dnp)-NH2 (RD, Catalog # ES002). The specific activity is >212 pmol/min/Mu g, as measured under the described conditions.
Gene Symbol: Ctss
Gene ID: 13040
Uniprot ID: CATS_MOUSE
Immunogen Region: Val18-Ile340
Immunogen: Recombinant Mouse Cathepsin S/CTSS Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val18-Ile340) of mouse Cathepsin S/CTSS (Accession #NP_067256.4) fused with and a 6×His tag at the C-terminus.
Immunogen Sequence: VCSVAMEQLQRDPTLDYHWD LWKKTHEKEYKDKNEEEVRR LIWEKNLKFIMIHNLEYSMG MHTYQVGMNDMGDMTNEEIL CRMGALRIPRQSPKTVTFRS YSNRTLPDTVDWREKGCVTE VKYQGSCGACWAFSAVGALE GQLKLKTGKLISLSAQNLVD CSNEEKYGNKGCGGGYMTEA FQYIIDNGGIEADASYPYKA TDEKCHYNSKNRAATCSRYI QLPFGDEDALKEAVATKGP
Function Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules and MHC class II antigen presentation. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L.
Protein Name Cathepsin S
Database Links Reactome: R-MMU-1474228
Reactome: -MMU-1679131
Reactome: -MMU-2022090
Reactome: -MMU-2132295
Reactome: -MMU-6798695
Cellular Localisation Lysosome
Secreted
Cytoplasmic Vesicle
Phagosome
Alternative Protein Names Cathepsin S protein
Ctss protein
Cats protein

Information sourced from Uniprot.org

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