SDS-PAGE gel of recombinant mouse Cathepsin C DPPI protein 3µg stained with Coomassie blue

Mouse Cathepsin C/DPPI protein (Recombinant) (His-Tag) (STJP019516)

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STJP019516
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Short Description :Recombinant-Mouse Cathepsin C/DPPI-His-Tag protein was developed from hek293 cells and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE/Enzyme Activity
Host:HEK293 Cells
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:0.5 mg/mL
Formulation:Liquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Endotoxin:< 1 EU per 1ug of protein (determined by LAL method)
Immunoreactivity:Specific activity is > 50, 000 pmol/min/ug and is defined as the amount of enzyme that hydrolyze 1pmole of Gly-Arg-AMC per minute at pH 6.0 at 37C.
Gene Symbol:Ctsc
Gene ID:13032
Uniprot ID:CATC_MOUSE
Accession Number:NP_034112.3
Immunogen:Mouse
Immunogen Region:25-462aa
Immunogen Sequence:DTPANCTYPD LLGTWVFQVG PRSSRSDINC SVMEATEEKV VVHLKKLDTA YDELGNSGHF TLIYNQGFEI VLNDYKWFAF FKYEVRGHTA ISYCHETMTG WVHDVLGRNW ACFVGKKVES HIEKVNMNAA HLGGLQERYS ERLYTHNHNF VKAINTVQKS WTATAYKEYE KMSLRDLIRR SGHSQRIPRP KPAPMTDEIQ QQILNLPESW DWRNVQGVNY VSPVRNQE
Tissue Specificity Broadly distributed, but higher levels found in lung, liver, kidney and spleen. Lower levels found in testis and brain.
Function Thiol protease. Has dipeptidylpeptidase activity. Active against a broad range of dipeptide substrates composed of both polar and hydrophobic amino acids. Proline cannot occupy the P1 position and arginine cannot occupy the P2 position of the substrate. Can act as both an exopeptidase and endopeptidase. Activates serine proteases such as elastase, cathepsin G and granzymes A and B.
Protein Name Dipeptidyl Peptidase 1
Cathepsin C
Cathepsin J
Dipeptidyl Peptidase I
Dpp-I
Dppi
Dipeptidyl Transferase Cleaved Into - Dipeptidyl Peptidase 1 Exclusion Domain Chain
Dipeptidyl Peptidase I Exclusion Domain Chain - Dipeptidyl Peptidase 1 Heavy Chain
Dipeptidyl Peptidase I Heavy Chain - Dipeptidyl Peptidase 1 Light Chain
Dipeptidyl Peptidase I Light Chain
Database Links Reactome: R-MMU-204005
Reactome: -MMU-2132295
Reactome: -MMU-5694530
Reactome: -MMU-6798695
Cellular Localisation Lysosome
Alternative Protein Names Dipeptidyl Peptidase 1 protein
Cathepsin C protein
Cathepsin J protein
Dipeptidyl Peptidase I protein
Dpp-I protein
Dppi protein
Dipeptidyl Transferase Cleaved Into - Dipeptidyl Peptidase 1 Exclusion Domain Chain protein
Dipeptidyl Peptidase I Exclusion Domain Chain - Dipeptidyl Peptidase 1 Heavy Chain protein
Dipeptidyl Peptidase I Heavy Chain - Dipeptidyl Peptidase 1 Light Chain protein
Dipeptidyl Peptidase I Light Chain protein
Ctsc protein

Information sourced from Uniprot.org

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