Tissue Specificity | Expressed in the inner and outer nuclear layers and the genglion cell layer of the retina. |
Post Translational Modifications | |
Function | Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1F gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, and by benzothiazepines. Activates at more negative voltages and does not undergo calcium-dependent inactivation (CDI), due to incoming calcium ions, during depolarization. |
Protein Name | Voltage-Dependent L-Type Calcium Channel Subunit Alpha-1fVoltage-Gated Calcium Channel Subunit Alpha Cav1.4 |
Database Links | |
Cellular Localisation | MembraneMulti-Pass Membrane Protein |
Alternative ELISA Names | Voltage-Dependent L-Type Calcium Channel Subunit Alpha-1f ELISA kitVoltage-Gated Calcium Channel Subunit Alpha Cav1.4 ELISA kitCacna1f ELISA kit |
output | |
Information sourced from Uniprot.org