| Host: | HEK293 cells |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Recombinant-Mouse Apolipoprotein A-I/APOA1-C-hFc protein was developed from hek293 cells and has a target region of C-hFc. For use in research applications. |
| Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Immunoreactivity: | Measured by its binding ability in a functional ELISA. Immobilized Mouse A-I/APOA1 at 5 Mu g/mL (100 Mu L/well) can bind Human MSR1/CD204 with a linear range of 1-21.4ng/mL. |
| Gene Symbol: | Apoa1 |
| Gene ID: | 11806 |
| Uniprot ID: | APOA1_MOUSE |
| Immunogen: | Recombinant Mouse Apolipoprotein A-I/APOA1 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Asp25-Gln264) of mouse ApoA-I/APOA1 (Accession #NP_033822.2) fused with a hFc tag at the C-terminus. |
| Post Translational Modifications | Glycosylated. Palmitoylated. May be acylated. Phosphorylation sites are present in the extracellular medium. |
| Function | Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. |
| Protein Name | Apolipoprotein A-IApo-AiApoa-IApolipoprotein A1 Cleaved Into - Proapolipoprotein A-IProapoa-I - Truncated Apolipoprotein A-I |
| Database Links | Reactome: R-MMU-114608Reactome: -MMU-1369062Reactome: -MMU-2168880Reactome: -MMU-3000471Reactome: -MMU-3000480Reactome: -MMU-381426Reactome: -MMU-8957275Reactome: -MMU-8963888Reactome: -MMU-8963896Reactome: -MMU-8963901Reactome: -MMU-8964011Reactome: -MMU-8964058Reactome: -MMU-9707616Reactome: -MMU-975634 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Apolipoprotein A-I proteinApo-Ai proteinApoa-I proteinApolipoprotein A1 Cleaved Into - Proapolipoprotein A-I proteinProapoa-I - Truncated Apolipoprotein A-I proteinApoa1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
