| Short Description : | MASPIN Blocking Peptide is synthetically produced from the 310-360 sequence and is suitable for use in western blot applications. |
| Applications: | Immunodepletion/Immunocompetition |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | SERPINB5 |
| Gene ID: | 5268 |
| Uniprot ID: | SPB5_HUMAN |
| Immunogen: | Synthetic peptide taken within amino acid region 310-360 on human MASPIN protein. |
| Immunogen Region: | 310-360 |
| Tissue Specificity | Normal mammary epithelial cells. |
| Function | Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. |
| Peptide Name | Serpin B5MaspinPeptidase Inhibitor 5Pi-5 |
| Cellular Localisation | SecretedExtracellular Space |
| Alternative Peptide Names | Serpin B5 proteinMaspin proteinPeptidase Inhibitor 5 proteinPi-5 proteinSERPINB5 proteinPI5 protein |
Information sourced from Uniprot.org