Applications: |
Immunodepletion/Immunocompetition |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Lysosomal acid lipase Blocking Peptide for STJ507784 is synthetically produced from the 200-250 sequence and is suitable for use in western blot applications. |
Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: |
LIPA |
Gene ID: |
3988 |
Uniprot ID: |
LICH_HUMAN |
Immunogen Region: |
200-250 |
Specificity: |
This blocking peptide is recommended for use in combination with Lysosomal acid lipase antibody, STJ507784 |
Immunogen: |
Synthetic peptide corresponding to amino acids within region 200-250 on Human Lysosomal acid lipase protein. |
Post Translational Modifications | Glycosylation is not essential for catalytic activity. |
Function | Catalyzes the deacylation of cholesteryl ester core lipids of endocytosed low density lipoproteins to generate free fatty acids and cholesterol. Hydrolyzes triglycerides (1,2,3-triacylglycerol) and diglycerides (such as 1,2-diacylglycerol and 1,3-diacylglycerol) with preference for the acyl moieties at the sn-1 or sn-3 positions. |
Peptide Name | Lysosomal Acid Lipase/Cholesteryl Ester HydrolaseAcid Cholesteryl Ester HydrolaseLalCholesteryl EsteraseDiacylglycerol LipaseLipase ASterol EsteraseTriacylglycerol Ester HydrolaseTriacylglycerol Lipase |
Database Links | Reactome: R-HSA-8964038 |
Cellular Localisation | Lysosome |
Alternative Peptide Names | Lysosomal Acid Lipase/Cholesteryl Ester Hydrolase proteinAcid Cholesteryl Ester Hydrolase proteinLal proteinCholesteryl Esterase proteinDiacylglycerol Lipase proteinLipase A proteinSterol Esterase proteinTriacylglycerol Ester Hydrolase proteinTriacylglycerol Lipase proteinLIPA protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance