KIF13A Blocking Peptide for STJ501535 peptide (STJ504279)

SKU:
STJ504279-250

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Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: KIF13A Blocking Peptide for STJ501535 is synthetically produced from the 1700-1800 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: KIF13A
Gene ID: 63971
Uniprot ID: KI13A_HUMAN
Immunogen Region: 1700-1800
Specificity: This blocking peptide is recommended for use in combination with KIF13A antibody, STJ501535
Immunogen: Synthetic peptide taken within amino acid region 1700-1800 on human KIF13A isoform a protein.
Tissue Specificity Widely expressed, with highest levels in heart, brain and skeletal muscle.
Function Plus end-directed microtubule-dependent motor protein involved in intracellular transport and regulating various processes such as mannose-6-phosphate receptor (M6PR) transport to the plasma membrane, endosomal sorting during melanosome biogenesis and cytokinesis. Mediates the transport of M6PR-containing vesicles from trans-Golgi network to the plasma membrane via direct interaction with the AP-1 complex. During melanosome maturation, required for delivering melanogenic enzymes from recycling endosomes to nascent melanosomes by creating peripheral recycling endosomal subdomains in melanocytes. Also required for the abcission step in cytokinesis: mediates translocation of ZFYVE26, and possibly TTC19, to the midbody during cytokinesis.
Peptide Name Kinesin-Like Protein Kif13a
Kinesin-Like Protein Rbkin
Database Links Reactome: R-HSA-390471
Cellular Localisation Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Midbody
Endosome Membrane
Golgi Apparatus Membrane
Recruited To The Midbody During Cytokinesis
Alternative Peptide Names Kinesin-Like Protein Kif13a protein
Kinesin-Like Protein Rbkin protein
KIF13A protein
RBKIN protein

Information sourced from Uniprot.org

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