KDM4C/GASC1/JMJD2C Blocking Peptide peptide (STJ504275)

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STJ504275-250
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Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : KDM4C/GASC1/JMJD2C Blocking Peptide is synthetically produced from the 500-520 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: KDM4C
Gene ID: 23081
Uniprot ID: KDM4C_HUMAN
Immunogen Region: 500-520
Immunogen: Synthetic peptide taken within amino acid region 500-520 on human JmjC domain-containing histone demethylation protein 3C protein.
Tissue Specificity Overexpressed in several esophageal squamous cell carcinomas (ESCs).
Function Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.
Peptide Name Lysine-Specific Demethylase 4c
Gene Amplified In Squamous Cell Carcinoma 1 Protein
Gasc-1 Protein
Jmjc Domain-Containing Histone Demethylation Protein 3c
Jumonji Domain-Containing Protein 2c
Histone H3-Trimethyl-L-Lysine(9 Demethylase 4c
Database Links Reactome: R-HSA-3214842
Reactome: R-HSA-5625886
Cellular Localisation Nucleus
Alternative Peptide Names Lysine-Specific Demethylase 4c protein
Gene Amplified In Squamous Cell Carcinoma 1 Protein protein
Gasc-1 Protein protein
Jmjc Domain-Containing Histone Demethylation Protein 3c protein
Jumonji Domain-Containing Protein 2c protein
Histone H3-Trimethyl-L-Lysine(9 Demethylase 4c protein
KDM4C protein
GASC1 protein
JHDM3C protein
JMJD2C protein
KIAA0780 protein

Information sourced from Uniprot.org

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