Name: Human WDR45 protein (Recombinant) (N-His) (STJP007832)
SKU: STJP007832
Availability: InStock

Human WDR45 protein (Recombinant) (N-His) (STJP007832)

SKU:

STJP007832

£208.50 - £1,163.50

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Short Description :	Recombinant-Human WDR45-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:	ELISA/Immunogen/SDS-PAGE/WB
Host:	E.coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Dilution Range:	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Function	Component of the autophagy machinery that controls the major intracellular degradation process by which cytoplasmic materials are packaged into autophagosomes and delivered to lysosomes for degradation. Binds phosphatidylinositol 3-phosphate (PtdIns3P). Activated by the STK11/AMPK signaling pathway upon starvation, WDR45 is involved in autophagosome assembly downstream of WIPI2, regulating the size of forming autophagosomes. Together with WIPI1, promotes ATG2 (ATG2A or ATG2B)-mediated lipid transfer by enhancing ATG2-association with phosphatidylinositol 3-monophosphate (PI3P)-containing membranes. Probably recruited to membranes through its PtdIns3P activity.
Protein Name	Wd Repeat Domain Phosphoinositide-Interacting Protein 4 Wipi-4 Wd Repeat-Containing Protein 45
Database Links	Reactome: R-HSA-1632852
Cellular Localisation	Preautophagosomal Structure Cytoplasm Diffusely Localized In The Cytoplasm Under Nutrient-Rich Conditions Localizes To Autophagic Structures During Starvation-Induced Autophagy
Alternative Protein Names	Wd Repeat Domain Phosphoinositide-Interacting Protein 4 protein Wipi-4 protein Wd Repeat-Containing Protein 45 protein WDR45 protein WDRX1 protein WDRXI4 protein WIPI4 protein JM5 protein

Information sourced from Uniprot.org

Model	Name	Host	Application
STJP010326	Mouse WDR45 protein (Recombinant) (N-His) (STJP010326)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP005172	Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172)	E.coli	SDS-PAGE/WB/ELISA/Immunogen
STJP004723	Human WAS protein (Recombinant) (N-His) (STJP004723)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP015118	Human TAS1R1 protein protein (Recombinant) (N-His) (STJP015118)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP014345	Human HBZ protein (Recombinant) (N-His) (STJP014345)	E.coli	ELISA/WB

Human WDR45 protein (Recombinant) (N-His) (STJP007832)

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