• Biotinylated Human ULBP-2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
  • The purity of Biotinylated Human ULBP-2 is greater than 95% as determined by SEC-HPLC.
  • Immobilized Biotinylated Human ULBP-2, His Tag at 1 Mu g/ml (100 Mu l/well) on the streptavidin precoated plate (5 Mu g/ml). Dose response curve for Human NKG2D, hFc Tag with the EC50 of 0. 2 Mu g/ml determined by ELISA.
  • Serial dilutions of Anti-NKG2D Antibody, hFc Tag were added into Biotinylated Human ULBP-2, His Tag : Human NKG2D, hFc Tag binding reactioins. The half maximal inhibitiory concentration (IC50) is 45. 2ng/ml.

Human ULBP-2 protein (Recombinant) (C-His-Avi) {Biotin} (STJP001680)

SKU:
STJP001680

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Host: HEK293
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human ULBP-2-C-His-Avi protein was developed from hek293 and has a target region of C-His-Avi. For use in research applications.
Conjugation: Biotin
Formulation: Lyophilised from 0.2 µm filtered PBS solution pH7.4.
Dilution Range: Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM
Storage Instruction: The lyophilized protein is stable for at least 1 year from date of receipt at-20°C.
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg).
Gene Symbol: ULBP2
Gene ID: 80328
Uniprot ID: ULBP2_HUMAN
Immunogen Region: Gly26-Ser217
Immunogen: DNA sequence encoding Human ULBP-2 including a C-His-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology.
Function Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity.
Protein Name Ul16-Binding Protein 2
Alcan-Alpha
Nkg2d Ligand 2
N2dl-2
Nkg2dl2
Retinoic Acid Early Transcript 1h
Database Links Reactome: R-HSA-163125
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Endoplasmic Reticulum
Secreted
In Cmv-Infected Fibroblasts
Detected In The Endoplasmic Reticulum/Cis-Golgi
Alternative Protein Names Ul16-Binding Protein 2 protein
Alcan-Alpha protein
Nkg2d Ligand 2 protein
N2dl-2 protein
Nkg2dl2 protein
Retinoic Acid Early Transcript 1h protein
ULBP2 protein
N2DL2 protein
RAET1H protein
UNQ463 protein
PRO791 protein

Information sourced from Uniprot.org

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