Human UBE2V2 protein (Recombinant) (N-His) (STJP014642)

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STJP014642-100
£503.50
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Host: E.coli
Applications: ELISA/WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human UBE2V2-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications.
Conjugation: Unconjugated
Formulation: Supplied as a 0.22 Mu m filtered solution in 50mm HEPES, 150mM NaCl, pH 7.0.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: < 1 EU/µg as determined by LAL test.
Gene Symbol: UBE2V2
Gene ID: 7336
Uniprot ID: UB2V2_HUMAN
Immunogen Region: Met1-Asn145
Immunogen: Homo sapiens (Human)
Function Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
Protein Name Ubiquitin-Conjugating Enzyme E2 Variant 2
Ddvit 1
Enterocyte Differentiation-Associated Factor 1
Edaf-1
Enterocyte Differentiation-Promoting Factor 1
Edpf-1
Mms2 Homolog
Vitamin D3-Inducible Protein
Database Links Reactome: R-HSA-5693565
Reactome: R-HSA-5693571
Reactome: R-HSA-5693607
Reactome: R-HSA-5696395
Reactome: R-HSA-69473
Reactome: R-HSA-8866654
Reactome: R-HSA-983168
Cellular Localisation
Alternative Protein Names Ubiquitin-Conjugating Enzyme E2 Variant 2 protein
Ddvit 1 protein
Enterocyte Differentiation-Associated Factor 1 protein
Edaf-1 protein
Enterocyte Differentiation-Promoting Factor 1 protein
Edpf-1 protein
Mms2 Homolog protein
Vitamin D3-Inducible Protein protein
UBE2V2 protein
MMS2 protein
UEV2 protein

Information sourced from Uniprot.org