| Short Description : | Recombinant-Human TXNL4A-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 0.5 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% Glycerol, 1mM DTT |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TXNL4A |
| Gene ID: | 10907 |
| Uniprot ID: | TXN4A_HUMAN |
| Accession Number: | NP_006692 |
| Immunogen: | Human |
| Immunogen Region: | 1-142aa |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MGSHMSYMLP HLHNGWQVDQ AILSEEDRVV VIRFGHDWDP TCMKMDEVLY SIAEKVKNFA VIYLVDITEV PDFNKMYELY DPCTVMFFFR NKHIMIDLGT GNNNKINWAM EDKQEMVDII ETVYRGARKG RGLVVSPKDY STKYRY |
| Post Translational Modifications | The disulfide bond seen in structures determined by X-ray crystallography and NMR is not essential for protein folding and function. |
| Function | Plays a role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes that are involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). |
| Protein Name | Thioredoxin-Like Protein 4aDim1 Protein HomologSpliceosomal U5 Snrnp-Specific 15 Kda ProteinThioredoxin-Like U5 Snrnp Protein U5-15kd |
| Database Links | Reactome: R-HSA-72163Reactome: R-HSA-72165 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Thioredoxin-Like Protein 4a proteinDim1 Protein Homolog proteinSpliceosomal U5 Snrnp-Specific 15 Kda Protein proteinThioredoxin-Like U5 Snrnp Protein U5-15kd proteinTXNL4A proteinDIM1 proteinTXNL4 protein |
Information sourced from Uniprot.org