Human TWIST2 protein (Recombinant) (N-His-SUMO & C-Strep) (STJP008096)

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STJP008096
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human TWIST2-N-His-SUMO & C-Strep protein was developed from e. coli and has a target region of N-His-SUMO & C-Strep. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: TWIST2
Gene ID: 117581
Uniprot ID: TWST2_HUMAN
Immunogen Region: Ser60-His160
Immunogen: Homo sapiens (Human)
Function Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of pro-inflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism. Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.
Protein Name Twist-Related Protein 2
Class A Basic Helix-Loop-Helix Protein 39
Bhlha39
Dermis-Expressed Protein 1
Dermo-1
Database Links Reactome: R-HSA-8878166
Cellular Localisation Nucleus
Cytoplasm
Mainly Nuclear During Embryonic Development
Cytoplasmic In Adult Tissues
Alternative Protein Names Twist-Related Protein 2 protein
Class A Basic Helix-Loop-Helix Protein 39 protein
Bhlha39 protein
Dermis-Expressed Protein 1 protein
Dermo-1 protein
TWIST2 protein
BHLHA39 protein
DERMO1 protein

Information sourced from Uniprot.org

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