Human TSSK6 protein (Recombinant) (His-Tag) (STJP018732)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human TSSK6-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol 0.4M urea |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TSSK6 |
| Gene ID | 83983 |
| Uniprot ID | TSSK6_HUMAN |
| Accession Number | NP_114426.1 |
| Immunogen | Human |
| Immunogen Region | 1-273aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Highly expressed in testis. Expressed at lower levels in colon, small intestine, ovary, prostate, thymus, spleen and peripheral blood leukocytes. |
| Post Translational Modifications | Autophosphorylated. Ubiquitinated.HSP90 activity negatively regulates ubiquitination and degradation. |
| Function | Serine/threonine-protein kinase component of the sperm flagellar doublet microtubules. May act as a regulator of sperm motility by mediating phosphorylation of sperm doublet microtubule proteins. Plays a role in DNA condensation during postmeiotic chromatin remodeling and histone-to-protamine transition during spermatogenesis. |
| Protein Name | Testis-Specific Serine/Threonine-Protein Kinase 6Tsk-6Tssk-6Testis-Specific Kinase 6Cancer/Testis Antigen 72Ct72Serine/Threonine-Protein Kinase SstkSmall Serine/Threonine Kinase |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonFlagellum AxonemeNucleusComponent Of The Sperm Flagellar Doublet MicrotubulesAlso Localizes In The Nucleus Of Elongating Spermatids |
| Alternative Protein Names | Testis-Specific Serine/Threonine-Protein Kinase 6 proteinTsk-6 proteinTssk-6 proteinTestis-Specific Kinase 6 proteinCancer/Testis Antigen 72 proteinCt72 proteinSerine/Threonine-Protein Kinase Sstk proteinSmall Serine/Threonine Kinase proteinTSSK6 proteinSSTK proteinFKSG82 protein |
Information sourced from Uniprot.org