Human TRPC6 protein (Recombinant) (N-His) (STJP006227)

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STJP006227
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Short Description :Recombinant-Human TRPC6-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol:TRPC6
Gene ID:7225
Uniprot ID:TRPC6_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Met1-Leu192
Post Translational Modifications Phosphorylated by FYN, leading to an increase of TRPC6 channel activity.
Function Forms a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Seems not to be activated by intracellular calcium store depletion.
Protein Name Short Transient Receptor Potential Channel 6
Trpc6
Transient Receptor Protein 6
Trp-6
Database Links Reactome: R-HSA-114508
Reactome: R-HSA-139853
Reactome: R-HSA-3295583
Reactome: R-HSA-418890
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Protein Names Short Transient Receptor Potential Channel 6 protein
Trpc6 protein
Transient Receptor Protein 6 protein
Trp-6 protein
TRPC6 protein
TRP6 protein

Information sourced from Uniprot.org