Human TRPC1 protein (Recombinant) (N-His) (STJP008094)

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STJP008094
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Host: E.coli
Applications: ELISA/Immunogen/SDS-PAGE/WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human TRPC1-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: TRPC1
Gene ID: 7220
Uniprot ID: TRPC1_HUMAN
Immunogen Region: Thr45-Lys386
Immunogen: Homo sapiens (Human)
Post Translational Modifications Activation of PRKCA induces phosphorylation of TRPC1 and subsequent Ca2+ entry into cells.
Function Forms a receptor-activated non-selective calcium permeant cation channel. Forms a heteromeric ion channel with TRPC4 or TRPC5 that has reduced calcium permeability compared to the homomeric TRPC4 or TRPC5 channel. Also permeable to monovalent ions including sodium, lithium and cesium ions. Isoform Short: Forms a receptor-activated non-selective calcium permeant cation channel. Also activated by intracellular calcium store depletion.
Protein Name Short Transient Receptor Potential Channel 1
Trpc1
Transient Receptor Protein 1
Trp-1
Database Links Reactome: R-HSA-3295583
Reactome: R-HSA-418890
Reactome: R-HSA-5578775
Reactome: R-HSA-983695
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Protein Names Short Transient Receptor Potential Channel 1 protein
Trpc1 protein
Transient Receptor Protein 1 protein
Trp-1 protein
TRPC1 protein
TRP1 protein

Information sourced from Uniprot.org

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